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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48e11f7d1cd70ebe7001afc804438c542c6bd479ec4e09f2ae03ed9f56f05c40' 
  AND token = 'd51dft3iN4ZXEFCMIOD2nMC0RURCSgkrtZnnbCtFWWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}