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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e387373ce864ca807d21240a5583d80d496e612ae3f4319794a7be81e7313c7' 
  AND token = 'JTv79lAwp/31hWPoiL2m5l4WV4/dgDI0b24byTMBTC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}