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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '383315802a19fb889c7911ee83a8a1d27e52879e3fe4a5f918e09f59d229d326' 
  AND token = '20O6EW4IpV3830OXvYexxkhpLkVX+mBPyS+MYpBN8PM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}