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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f0f48db2cfa4e72aa89dac5ee9593b55c725fa870db237f58a8b584e765e42d' 
  AND token = '+YxVSh6FcNamcfnYZzh5QGiP3pq0u5oCcmQCMXhR5Qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}