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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '435b04f1fe2e9a39965604eb1ceab8e3067a0eb282081e9c42489d10c1dc2e10' 
  AND token = 'EZ8W/urNOtORdhgvtRKYe5VuA1IfxfbW6nGUK0y7bmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}