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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20bdfe2cc8828865228328fabc1f1b0e8c9b990b8a284a3bba4ed88c3c52501d' 
  AND token = 'xsLKIFAKeeZ5iKyg1tvOo0YNTUgs4+EjUPrOKnv3AlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}