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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef609346b65f5859b8343513ccab94d064ae800e002cbee5d7aa88b777a135ac' 
  AND token = 'rM0Dfg/lS3tH3kSy1E6X7qyS2bwCPeHoUk6JE4nzQ58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}