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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e39a64aa4ebb359891121089340da1cc5a2c87f201d829750e3edac6c49d6c4' 
  AND token = 'QHRil+KelCnscUkxeIvm++y2fd9QENlYsG6fCnBS2NQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}