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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ab89b7cb395130c75fd397e5b0a1d842bcc79eabdd9905bcb4833c19e60cb88' 
  AND token = 'u0d7WIeabM+VWWfcS01vKNSwCGxEoIT4BKbX3bJ9T7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}