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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cda85d7fc995a3f02182e41268db6321990ccdd0642530d96e9b7fa20142c578' 
  AND token = '4nADbhpCR4h5mm84oiULKxw5u3AEbsSPlCCWlrLSwnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}