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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b33fdbb71c7f211c3f7bf45255e0c8ba17d7f6f6fd63e9a8ede386deb5175250' 
  AND token = 'uqb6Y97CbSYeMy0Jxm4lQoPQmibH59rSH2SLWpwzbsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}