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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e51373695f1c1fdab67fb20751ea10d867a71d70f5c238393120ea122d0adbb5' 
  AND token = 'F0PSLiedMRozKpRcb+tP52DO7yp27CvzLmq0XtdOtpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}