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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17d462afe166e127c5797aca02e9f42bc016021eec636a1489130e08db452475' 
  AND token = 'YUMi9TZij8ifRpaQt8G3CAs+LGU30lqCQBncbKbY6ZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}