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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a234c46f8839f3e6311e2d46c6bca2fa3ef5b39a89439a01490af202080e528' 
  AND token = 'bl2Ypg369hUbSdoaO135gzRIoHNlNpgaOOf0duRS9iI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}