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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73f0b9a8415b8c1ab37b0e5fcffc2abb4fb99440015bbd5d199e891ff6428288' 
  AND token = 'J+2WjQE8w2vRG1rrSis8soVwpL3MivaKsLUF4IqH+3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}