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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34eb9ca38943aff19f2f884659444907983fcca0d395cd7ff2e5e4172f832b2a' 
  AND token = 'vwRERA3mJDNW3pPLcCXoE22r1RRmrR+WfOb+rB7AZBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}