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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6abce303cf26c6a3bfdd85056c2b150fe35bd7a0884b9faa9cc2d390c165f8f' 
  AND token = 'hgUixx+CjkD82Im6uYOxb3DSKImBzfsm1lVW0pJ2nVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}