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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b458525eb7b7cc66e709310bd81f3f59e6566dcb7cb5f4f14771579421e032f' 
  AND token = 'zf6MFEih+vOHj80Xk+EPU+sGxB/W5DpRpoi4yQv3P5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}