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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8c1abf8dee0226bb70258db71abd0514d5732b9078a64cf340705db081a0595' 
  AND token = 'u58aY9UsXrApQDbpSE/1FLLY8TmbXUyaoMUPHWF2wn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}