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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '273aab91d3adb409eae634cd8f8e42502765012c2828b34cef1842fef5b60ecd' 
  AND token = 'I0+eog64Ma9QGnz3j0s9yC1GRLAVILemYTGEnX5vh9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}