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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '585c0524db1cb507e102b6d0b81bd3764badfcb96e6c832396b324839d6b8ed2' 
  AND token = '7pm6B3dUaDEb1YHlvewXakp8cq8bAe6Or5+WzjWHjPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}