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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e1f3e07299c8f2d5677c6198228e183913c6a2a824b8e4de531952bb796b279' 
  AND token = '+90gWSpKxa8ZYLQ5G0HUStF+iZbu2WHEgEUgBTM4EjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}