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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a8bcfb3d100c0930299502e9faae16b03c0d26bb157c1ab4b20bdd89ef03a90' 
  AND token = '2CuhFW4RRMkqxJqkk5B/3agTbrZvJJNxvsg6u/Uhgt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}