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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c39d1098046e33a56d84b216517149a5c23d0f1aa26fe42899beea624f4b126d' 
  AND token = 'LD29UKzy6K6AUMES+xwn+bwlJEY/GAzWPxFHS1aeTx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}