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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc8287cc7b25899ea6962d3ea9a544875e1c471be908c607c32706907470c533' 
  AND token = 'DjpQ1bAZqPjuWVnfE+Fey+pAi3ax8okrrczrf+0+bkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}