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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ee4d1bdae825d2fc63c5083f1d34a13dd57334518401b024aa66ba4b5df3bfd' 
  AND token = 'BQq0cPJrffkYxQaOD/KWAo3as0jfZkjUI/W6lnVXJNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}