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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1442dd00f789e053dc1a71a0eb73f5e9ca3d05ff27395c8eedcf614baeb0c2ef' 
  AND token = 'HHy04dyTLK3XHvl33QRxxOrQ2/pTq9FZ5zkYkEhVSDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}