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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6600d34a3786f3fdca036dfc08bb4ccdb4bbead3b6a0473d953b006cd07f3f8f' 
  AND token = 'qC1RUPEXmHQsT1UZMPQW7lQ+out+9pmZIITc09mSfzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}