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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72f37860d8e89b87e7fd0204125149963d1568a741b97db74fd53cf7d7499290' 
  AND token = 'rnqJFXQBGMQLrsDQO/xrJT8M2upAUB20Z/EfGxZR68o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00394

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}