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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f499c15aeed6f1bb9300a0151c0a76a2f2bdfa89d9e69f781403f1d2b669c2b2' 
  AND token = 'IwMbOsDjsa9dXtT4rveGnL8Cs8s33ZOIeO5sinUdsGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}