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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8c2ce461d20002b99c4dc38e74ed436d8acce162b812d5000d41f444b190a94' 
  AND token = 'L0gOLsR+97AysbJAmTWJ63gDyK8DnfJjsBCHjXKgoFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}