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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '745b5b68545a222c71ea5eaeb978cf8db12f52beb1fea9c9948c86d0edc84004' 
  AND token = 'pW+SvFKStFZ36Jjoyes172VBd4XkkqJgEcMmm3vXWmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}