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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dec7cc6a1dba97d32b1debc247416f0f6e0d59a7599c57096d39035ff4fb2ac' 
  AND token = 'k85cEyCo+LhgWt1MJYakltNuJ2R/pY+0LkDDIMwnSrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}