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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '217b154abaf9a272acd630e6835f7f2d5f3463d5a385a1628ed5af26b991129e' 
  AND token = 'Nruinjl1BNbfIkih/xB3jSmqo3f1JZPO2LPBJ882qZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}