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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '888ddc6d4f24ad236f7860078416b6e2ea9b36eaa38761293466dd1dd50d890d' 
  AND token = '20IqM5z2PnahaEuBNssYjj9hylh+2MCjaHu+Xi5Nq5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}