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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77f46cdfebe5adb455bf42a9e6f9c629f9ba4df8d2a28d93c2e848d0b7688157' 
  AND token = 'CiJoq/n9wUzP5fILA+C08G8OPQG9uyyTLzjgGAuk4c0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}