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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e06b22cdce938ab06177811b26b42a587cdc9c05c0d6ad7db8efb80f7bd609b4' 
  AND token = 'ZfOe1ZPLVdmijb1zOBcK7olJ5jCSrBjd3DEZ1tr60VI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}