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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5f855ecaf9a591b9aa84250d8f3e1e9d9486722f4b5eb3216c13165011eb349' 
  AND token = 'ZXduXn7g1wYVcdssUD8g/k5hk2ME3923NcBElM2NAz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}