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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53d1755e3f3612ba0b4a2b9c7a980f4a2dec9fd05130cea2229aa1652a52cac5' 
  AND token = 'GXfxzpwViBGoZJ8TBziXPVcIslzbc7xLrjqUCmcHppU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}