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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f4a4b63b994d41e01c4c2a31bdca55544b4e2d88031b92c16b44d9878c85f37' 
  AND token = 'V9fxYS1AGCcmjeAIxVwPDmPcOAMcOIgfp+9VucMC6TE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}