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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5481e3655d181436106d509329e1820ac075ad43bd0cdf7651b7229d591864ec' 
  AND token = 'ma5Jcd55tFpO6SneZsGrJHmcEMoYWA/vmi19TJkxRFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}