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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fd378d4209a84b9e7da63a10b5bcbc0ca7142bccf426d3e52199b6e0ea622bc' 
  AND token = 'nFJwV2b89RD0sv88YVg/flrfY9iOZBWR7LgpmbNkiac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}