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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9e83292e31fe0f8bc1b81a7eba7d78a700a713029531ba2d7ede7ff92ca2615' 
  AND token = 'eHy2wZiFwAx3mns+klWxW+CpT7bLT0Lb87xc5FHNxvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}