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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '446c87c948db7c4c46d0c88324a67313f7c15b69d9517e9d8285a42c1f9cd379' 
  AND token = 'BUVmOEXli9o04gSy/0dr0VfSKEX9Q8Qoywoaa3HQH6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}