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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c107e1e09edf6401cedcb0e8a754f714295263278752a9a0035f22d3eedf34c2' 
  AND token = 'ioZ/Rkq6qIznn6C5c85ZLtrC7DWX89IRpgMCLpMoGS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}