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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f801939d8e21704fdd090ae3cf0ceb5061b4a1f0a011d58b7ab04dec27e2b351' 
  AND token = 'YkmE2mL3E7XjMv79+cJC0OioI53GTx5WtjaArJy0yjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}