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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db90e0ca3f6473f5cec3513e661383e62cd19c5582075f814af865997bf88a6f' 
  AND token = 'K8dUHrJwgnf0kEtXtQBFBm4kVlmtyLcxmmWCG9Rmea0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}