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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7eac062c145f0e054376f2b74eed9fd5aed8408d1a877ee9f4f8e1dc3ee4d1b9' 
  AND token = 'EDVSOnPSl9L9M0M+Tp75h8tWaL8n8ljt09fQ9uYCmxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}