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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a40e5d7df5cc42b6922685391079df69f128aed75f0241aad8e0d036e2976de4' 
  AND token = 'TDf+zPgkXac2a2HMvNt7y/CXNrvcpNi+Jl/0azKFjDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}