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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22fb7e2c17293d99616bd6fce12e15aa22036e67f776d2b24d1c6cd8397d90c2' 
  AND token = '2nnX+NEn3PdWW21TpiMppwhxN6IcuUbFLKgw/OT+LjQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}